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  1. Gasotransmitters

    There are many gaseous chemicals with effects/functions in the human body, however only three of these act as bona fide 'gasotransmitters' (or gaseous transmitters): nitric oxide (NO, a free-radical mediator), carbon monoxide (CO) and hydrogen sulfide (H2S). These three regulate a variety of key biological functions and are also implicated in tumour biology. They can have endocrine, paracrine, and autocrine actions. They are produced enzymatically under tight regulation. They have varying biological half-lives, which affects their mode of transmitter action.

    efaccena - 29/03/2016 - 1:08pm

  2. ANS Part II: Receptors, transmitters and drugs

    The two principal (or 'classical') small transmitter molecules used by neurons of the motor ANS are acetylcholine (ACh) and noradrenaline (NA).

    efaccena - 01/09/2017 - 10:39am

  3. Other chemical mediators

    There is wide variation in the structure and function of the different types of endogenous molecules which act as signal transmitters, from tiny gasses such as nitric oxide and carbon monoxide (sometimes referred to collectively as gasotransmitters), through neurotransmitters to peptide hormones and growth factors.

    media - 23/05/2014 - 10:24am

  4. Ischemic heart disease

    Oxygen demand of the heart dynamically changes, and the coronary artery can adjust its blood flow to fulfill the myocardial oxygen demand (coronary blood flow reserve). Normally, the oxygen supply and the oxygen demand are well balanced in healthy subjects. When the oxygen supply to the heart becomes inadequate for the needs of the heart, myocardial ischemia occurs. That is, ischemic heart disease (IHD) is caused by an imbalance between the oxygen supply (coronary blood flow) and the oxygen demand of the heart.

    efaccena - 13/02/2018 - 10:14am